"It is the source of all our problems. Since impermanence spells anguish to us, we grasp onto things desperately, even though all things change. We are terrified of letting go, terrified, in fact, of living at all, since learning to live is learning to let go. This is the tragedy and the irony of our struggle to hold on. For not only is it impossible to do so, but it brings us the very pain we’re seeking to avoid."